A 32-Year-Old Woman with Leg Weakness

A 32-Year-Old Woman with Leg Weakness

A 32-year-old woman has noticed increasing weakness and numbness in her legs over the past few days, and she is feeling short of breath when she walks. Three weeks ago, she had diarrhoea whilst on holiday, and stool culture confirmed infection with Campylobacter...
A 55-Year-Old Woman with Tiredness and Depression

A 55-Year-Old Woman with Tiredness and Depression

You review a 55-year-old woman with a 6-month history of feeling tired and depressed. She has been constipated for the past 3-months, for which she is taking 15 ml of lactulose twice daily. She is otherwise fit and well and has no past medical history of note. You...
A 9-Month-Old Baby with Failure to Thrive

A 9-Month-Old Baby with Failure to Thrive

A 9-month-old baby boy is brought to your surgery by his mum, who is concerned about his weight gain. His red book measurements have dropped from above the 50th centile to below the 25th centile over the past 4 months. He has had several chest infections, and mum...
Family Planning in Sickle Cell Disease

Family Planning in Sickle Cell Disease

A West African couple present to your surgery, they are planning on having a baby, but they are both known to be sickle-cell trait. They have come to discuss the chances of their baby being affected by the disorder. 1. How is sickle-cell disease inherited? Show Answer...
A 21-Year-Old Woman with an Intensely Itchy Rash

A 21-Year-Old Woman with an Intensely Itchy Rash

A 21-year-old woman develops a rash on her forearms shortly after spending the afternoon washing up at a restaurant where she has just started working. The rash is very itchy, but she has no other symptoms and feels well otherwise. The rash is shown below: 1. What is...
A 70-Year-Old Man with Severe Leg Pain

A 70-Year-Old Man with Severe Leg Pain

A 70-year-old man presents to the ED having developed sudden onset severe pain in his right leg. This occurred whilst he was watching television 1 hour earlier. On examination he is distressed, and his right leg is pale in appearance. His right foot feels cold to...

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