Articles

Acute Epiglottitis

Acute Epiglottitis

Acute epiglottitis is inflammation of the epiglottis. When there is involvement of the soft tissues surrounding the epiglottis, then it is referred to as acute supraglottitis. It can result in life-threatening airway obstruction and death if rapid treatment is not...

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The Russian Plague of 1770-1772

The Russian Plague of 1770-1772

In the summer of 2016 a 10-year-old Russian boy cut himself skinning a marmot whilst hunting with his grandfather in the remote Kosh-Agach region in the Atlai Mountains. A few days later he developed a fever and a flu-like illness and was taken to a local hospital. He...

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Managing Hypertension in Primary Care

Managing Hypertension in Primary Care

Hypertension is one of the most important risk factors for premature morbidity and mortality in the UK. It is a major risk factor for stroke, myocardial infarction, heart failure, cognitive decline and premature death. A recent JAMA paper from 2018 labelled...

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Osteoporosis Update Part 1 – Assessing Risk

Osteoporosis Update Part 1 – Assessing Risk

Osteoporosis is a progressive systemic skeletal disease characterised by low bone mass and structural deterioration of bone tissue. Consequently, bone fragility is increased and there is increased susceptibility to fracture. Osteoporotic fragility fractures are...

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Diagnosing Pneumonia on Chest X-Ray

Diagnosing Pneumonia on Chest X-Ray

Pneumonia, which is defined as inflammation of the lung, is a common cause of morbidity and mortality around the world. Every year between 0.5% and 1% of adults in the U.K. will develop community-acquired pneumonia. Pneumonia is characterised by exudation and...

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Drugs in Pregnancy

Drugs in Pregnancy

Drugs are now used in over half of all pregnancies and the prevalence of their use is steadily increasing. Some of the most commonly prescribed drugs include analgesics, antiemetics, antimicrobials and antihistamines. In addition to this the use of social and illicit...

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Interpreting Abnormal Liver Function Tests

Interpreting Abnormal Liver Function Tests

Dealing with a patient with abnormal liver function tests (LFTs) in the primary care setting is an extremely common clinical scenario. Approximately 20% of all LFTs are abnormal, of which less than 10% can be explained by existing disease. LFTs are not specific to...

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The Mysterious Sweating Sickness

The Mysterious Sweating Sickness

The Middle Ages are renowned for being a turbulent and difficult period of history. War, famine and disease occurred throughout the period and one of the most devastating pandemics in history, the Black Death, occurred in the mid 14th century. The Black Death was not...

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The Lowdown on Lyme Disease

The Lowdown on Lyme Disease

Lyme disease is caused by the spirochete bacterium Borrelia burgdorferi. It is transmitted to humans through the bite of infected Ixodes spp. ticks. In high-risk areas, it is estimated that as many as 40% of ticks can be infected. The incidence of Lyme disease is...

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