Articles

Sepsis

Sepsis

Sepsis is one of the leading causes of death worldwide but remains a little-known entity to the general public. Every year, around 245,000 people in the UK develop sepsis, and of those, over 48,000 die. The incidence of sepsis in the developed world is increasing by...

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The Immortal cells of Henrietta Lacks

The Immortal cells of Henrietta Lacks

On January 29th, 1951, a young African-American woman named Henrietta Lacks presented to the Johns Hopkins Hospital in Baltimore. She had been experiencing discomfort in her abdomen, which she described as a “knot” in her womb. Four and a half months earlier, she had...

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Ingested Foreign Bodies: An Overview

Ingested Foreign Bodies: An Overview

The ingestion of foreign bodies is a common problem that presents frequently to Emergency Departments. Although it can affect any age group, it is most frequently seen in young children between 6 months and 5 years. Coins are the most commonly swallowed objects, but...

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Nerve Agents: Recognition and Management in Clinical Practice

Nerve Agents: Recognition and Management in Clinical Practice

Nerve agents, sometimes called nerve gases, are among the most toxic chemical warfare agents known. Originally developed during and after World War II, they are potent inhibitors of acetylcholinesterase and can cause rapid systemic collapse if not promptly managed....

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Cyanotic Congenital Heart Disease: A Radiologist’s Guide

Cyanotic Congenital Heart Disease: A Radiologist’s Guide

Cyanotic congenital heart disease (CHD) typically involves right-to-left or mixed circulations, resulting in systemic desaturation. In adult imaging, most cases you encounter will be in patients with repaired or palliated anatomy. Others may present with long-standing...

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Acyanotic Congenital Heart Disease: A Radiologist’s Guide

Acyanotic Congenital Heart Disease: A Radiologist’s Guide

Acyanotic congenital lesions are among the most frequently encountered cardiac abnormalities in adult imaging. Many are picked up incidentally, while others represent the long-term sequelae of childhood repairs. Sometimes, the diagnosis isn’t made until adulthood,...

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Ischaemic Bowel 

Ischaemic Bowel 

Ischaemic bowel disease occurs when there is inadequate blood supply to the intestines, leading to mucosal injury, necrosis, and perforation if untreated. It is a life-threatening emergency with high mortality, particularly in cases of bowel infarction. There are two...

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Pertussis

Pertussis

Pertussis, also known as whooping cough, is an upper respiratory tract infection caused by the Gram-negative bacteria Bordatella pertussis. Transmission is via respiratory droplets, and the incubation period is approximately 7-21 days. The disease is highly contagious...

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Anticholinergic Poisoning

Anticholinergic Poisoning

Anticholinergic poisoning is a potentially life-threatening toxidrome that occurs following exposure to substances that block acetylcholine at muscarinic and, to a lesser extent, nicotinic receptors. It can result in profound central and peripheral effects, ranging...

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