Hyperthyroidism

Hyperthyroidism

Hyperthyroidism is a clinical syndrome that results from an excess of circulating thyroid hormones. It is more common in women, and the incidence increases with age. In Europe, it affects approximately 1 in 2,000 people annually.   Aetiology Hyperthyroidism can...
Hypothyroidism

Hypothyroidism

Hypothyroidism is a clinical syndrome that results from a deficiency of circulating thyroid hormones. It affects women more commonly than men and is most frequently seen in the over 60s. The term myxoedema refers to a more severe form of the syndrome where there has...
Parkinson’s Disease Update

Parkinson’s Disease Update

Parkinson’s disease (PD) is a progressive neurodegenerative condition resulting from the death of the dopamine-containing cells of the substantia nigra.   Epidemiology Parkinson’s disease is the second most common neurodegenerative disorder after...
Acute Epiglottitis

Acute Epiglottitis

Acute epiglottitis is inflammation of the epiglottis. When there is involvement of the soft tissues surrounding the epiglottis, then it is referred to as acute supraglottitis. It can result in life-threatening airway obstruction and death if rapid treatment is not...
The Russian Plague of 1770-1772

The Russian Plague of 1770-1772

In the summer of 2016 a 10-year-old Russian boy cut himself skinning a marmot whilst hunting with his grandfather in the remote Kosh-Agach region in the Atlai Mountains. A few days later he developed a fever and a flu-like illness and was taken to a local hospital. He...
Managing Hypertension in Primary Care

Managing Hypertension in Primary Care

Hypertension is one of the most important risk factors for premature morbidity and mortality in the UK. It is a major risk factor for stroke, myocardial infarction, heart failure, cognitive decline and premature death. A recent JAMA paper from 2018 labelled...

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