Cytochrome p450 Enzymes and Drug Metabolism

Cytochrome p450 Enzymes and Drug Metabolism

Many drugs are metabolised in the liver. Drugs are either metabolised by phase I reactions (oxidation, reduction, or hydrolysis) or phase II reactions (e.g. glucuronidation). Phase I reactions are mainly carried out by the cytochrome P450 family of isoenzymes, of...