


Pertussis
Pertussis, also known as whooping cough, is an upper respiratory tract infection caused by the Gram-negative bacteria Bordatella pertussis. Transmission is via respiratory droplets, and the incubation period is approximately 7-21 days. The disease is highly contagious...
Anticholinergic Poisoning
Anticholinergic poisoning is a potentially life-threatening toxidrome that occurs following exposure to substances that block acetylcholine at muscarinic and, to a lesser extent, nicotinic receptors. It can result in profound central and peripheral effects, ranging...
Understanding Adverse Drug Reactions
Adverse drug reactions (ADRs) are a significant concern in clinical practice, impacting patient safety and treatment outcomes. The World Health Organization (WHO) defines an ADR as “A response to a drug which is noxious and unintended, and which occurs at doses...
Myxoedema Coma
Myxoedema coma is an extreme manifestation of untreated hypothyroidism and is a life-threatening condition characterised by hypometabolism and altered mental status. It commonly affects elderly patients with long-standing hypothyroidism, often precipitated by...