Compartments and Fluid Spaces in Health
The amount of water in the body varies with a patient’s age, weight, and sex. Total body water (TBW) accounts for around 60% of an adult male’s total body weight; a normally hydrated 75 kg man will consist of approximately 45 L of water. There are two major fluid...
Dr. Joseph Bell: The Real Life Sherlock Holmes
I have been fascinated with the detective Sherlock Holmes since childhood. His almost supernatural powers of observation and deduction in stories such as ‘The Sign of the Four’, ‘The Speckled Band’, and ‘A Study in Scarlet’ captivated me and I have re-read them many...
Hyperthyroidism
Hyperthyroidism is a clinical syndrome that results from an excess of circulating thyroid hormones. It is more common in women, and the incidence increases with age. In Europe, it affects approximately 1 in 2,000 people annually. Aetiology Hyperthyroidism can...
Hypothyroidism
Hypothyroidism is a clinical syndrome that results from a deficiency of circulating thyroid hormones. It affects women more commonly than men and is most frequently seen in the over 60s. The term myxoedema refers to a more severe form of the syndrome where there has...
Parkinson’s Disease Update
Parkinson’s disease (PD) is a progressive neurodegenerative condition resulting from the death of the dopamine-containing cells of the substantia nigra. Epidemiology Parkinson’s disease is the second most common neurodegenerative disorder after...
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