HELLP Syndrome

HELLP Syndrome

HELLP syndrome is a pregnancy complication that usually presents in women who have pre-eclampsia or eclampsia. Affected women also show signs of liver damage and abnormalities in blood clotting. HELLP syndrome is characterised by: Haemolysis ELevated liver enzymes Low...
What is Evidence-based Medicine?

What is Evidence-based Medicine?

Evidence-based medicine is the term used to describe the process of systematically reviewing, appraising and using the findings of clinical research to assist with the delivery of optimum clinical care to patients. The most commonly quoted definition of evidence-based...
The Story of Penicillin

The Story of Penicillin

I sometimes take antibiotics for granted. As a doctor, I have prescribed thousands of courses of antibiotics throughout my career. I have taken many courses myself also, and they almost certainly saved my life when I perforated my appendix in my mid-20s. Antibiotics...
The Menopause

The Menopause

The menopause is the biological stage in a woman’s life when menstruation permanently ceases. It marks the end of the female reproductive life. It occurs with the final menstrual period and is usually diagnosed clinically after 12 months of amenorrhoea. In the UK, the...
Maternal Changes During Pregnancy

Maternal Changes During Pregnancy

Pregnancy is a period of profound physiological transformation. The mother’s body undergoes wide-ranging adaptations across virtually all organ systems, designed to support foetal growth, prepare for labour, and safeguard maternal well-being. These changes are...
Pregnancy

Pregnancy

Pregnancy, also referred to as gestation, is the period during which one or more offspring develop inside the uterus. It typically lasts around 40 weeks from the first day of the last menstrual period (LMP) and is divided into three trimesters. The first...