Major Incident Management Part 1 – At the Scene

Major Incident Management Part 1 – At the Scene

A major incident is an incident (or series of incidents) causing casualties on a scale beyond the normal resources of the emergency and healthcare services’ ability to manage. The Major Incident Medical Management and Support (MIMMS) manual states that a major...
Phases of Clinical Research

Phases of Clinical Research

Bringing new drugs onto the market The process of bringing new drugs (or other health interventions) onto the market is long and arduous and, in some cases, can take years or even decades. Developing any new drug begins by developing an understanding of the disease or...
Lung Volumes and Capacities

Lung Volumes and Capacities

Lung volumes, which are also known as respiratory volumes, refer to the various volumes of gas in the lungs at any given time during the respiratory cycle. Lung capacities are derived from a summation of different lung volumes. It is important to have an understanding...
The Diagnosis and Management of Atrial Fibrillation

The Diagnosis and Management of Atrial Fibrillation

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia seen in clinical practice. It is a perennial hot topic in medicine and remains a very common source of exam questions. The diagnosis and management of AF presents some serious challenges, and...
The Renin-Angiotensin-Aldosterone System

The Renin-Angiotensin-Aldosterone System

The renin-angiotensin-aldosterone system (RAAS) is a hormonal system that is responsible for the regulation of arterial blood pressure and of the concentration of sodium in the plasma.   Renin and angiotensinogen The first stage of the RAAS is the release of the...
Stroke and Transient Ischaemic Attack

Stroke and Transient Ischaemic Attack

The latest guidance from NICE for the management of stroke was keen to highlight the fact that it is both preventable and treatable and not merely an inevitable consequence of ageing. Stroke is defined by the World Health Organization as a clinical syndrome consisting...