Addison’s Disease

Addison’s Disease

Addison’s disease (primary adrenal insufficiency) is caused by the underproduction of the steroid hormones by the adrenal glands. Glucocorticoid, mineralocorticoid and sex steroid production are all affected. It is more common in women than in men and most commonly...
Hyperaldosteronism

Hyperaldosteronism

Hyperaldosteronism occurs when there are excessive circulating levels of aldosterone. Hyperaldosteronism can be subdivided into two main types: Primary hyperaldosteronism (~95% of cases) Secondary hyperaldosteronism (~5% of cases)   Primary hyperaldosteronism is...
A 61-Year-Old Man with Widespread Hyperpigmentation

A 61-Year-Old Man with Widespread Hyperpigmentation

A 61-year-old man presents with generalised weakness and skin hyperpigmentation. His only past medical history of note is a bilateral adrenalectomy for Cushing’s syndrome 18 years earlier. On examination of his visual fields you discover a bitemporal hemianopia. 1....

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