The Recognition and Management of Sepsis

The Recognition and Management of Sepsis

Sepsis is one of the leading causes of death worldwide but remains a little known entity to the general public. Every year, around 150,000 people in the UK develop sepsis and, of those, over 40,000 die. The incidence of sepsis in the developed world is increasing by...
Hepatitis B Serology and Vaccination

Hepatitis B Serology and Vaccination

Hepatitis B is an infection of the liver caused by the hepatitis B virus (HBV), a double-stranded DNA virus of the Hepadnaviridae family that replicates by reverse transcription. Hepatitis B is the most common cause of hepatitis globally, and the World Health...
Understanding Vaccination

Understanding Vaccination

Vaccination is the administration of antigenic material (the vaccine) to stimulate an individual’s immune system to develop adaptive immunity to a particular pathogen. Herd immunity is a type of indirect protection from infectious disease that occurs when a...
A Patient with Troublesome Acne

A Patient with Troublesome Acne

You review a patient with moderately severe acne that has been treated with a variety of topical agents over the past 6 months. There has been a poor response treatment and you consider switching to an oral antibiotic. You are aware that there is an increasing issue...
Understanding Hyponatraemia

Understanding Hyponatraemia

Hyponatraemia is the most common electrolyte disorder encountered in clinical practice and is seen in approximately 30% of hospitalised patients. It is also one of the most poorly understood and difficult to manage scenarios in medicine. It is rarely dangerous, but on...